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APION

APION

Ion exchange polymer

The ION exchange cross-linked polymers known as APION have shown to be efficient and secure excipients that give formulation flexibility and a special solution to issues like API disintegration and taste masking. For the purpose of masking taste and promoting patient compliance, suspension formulations include ion exchange polymers. Ion Exchange polymers, with their great performance and reproducibility, also gain prominence in the oral solid disintegration segment over time.

Types/Series

Based on their application, APION’s are categorized in to three range of categories:

APION T series

  • APION T 51
  • APION TA 42
  • APION TC 42

APION A Series - Coming Soon

  • APION A 04
  • APION A 48
  • APION A 50

APION D Series

  • APION DF 44
  • APION DM 44
  • APION DT 44

APION T series

Grade Generic Name Physical Form Functional Group Ionic Form Moisture Content Application
APION T51 Polacrilex Resin Powder -COO- H+ NMT 5.0 Taste Masking of Bitter Drug, Dextometharphan HBr, Psudoefldrive HCl, Norfloxacine, Ofloxacine, Dicyclomine HCl Key raw material for Nicotine Polacrilex USP Stabilization of Vitamine B12
APION TA42 Weak Cationic Exchange Resin Powder -COO- K+ NMT 10 Taste Masking of Bitter drugs like Azithromycin Di-Hydrate
APION TC42 Weak Cationic Exchange Resin Powder -COO- H+ NMT 5.0 Taste Masking of Bitter drugs like cefpodoxime proxeti
APION Dt44 Polacrilin Potassium USP Powder -COO- K+ NMT 10 Taste Masking of Bitter drug like Ciprofloxacine HCl, Roxithromycine, Chloroquine Phosphate, Zinc Gluconate, Pyrimethamine, Tadalafile, Zinc Sulphate

APION A Series - Coming Soon

Grade Generic Name Physical Form Functional Group Ionic Form Moisture Content Application
APION A04 Sodium Polystyrene Sulphonate USP Buff / Brown Powder -SO3- Na+ NMT 10 Sustained / Delayed Release of Drugs like Dextromethaphran HBr, Psudoefidrine HCl Treatment of Hyperkalamia
APION A48 Calcium Polystyrene Sulphonate BP/JP Cream Powder -SO3- Ca++ NMT 10 Sustained / Delayed Release of Drugs like Dextromethaphran HBr, Psudoefidrine HCl Treatment of Hyperkalamia
APION A50 Cholestyramine Resin USP White Powder -N+ R3 Cl- NMT 12 Cholesterol Reduction

APION D Series

Grade Generic Name Physical Form Functional Group Ionic Form Moisture Content Application
APION DF44 Polacrilin Potassium USP Powder -COO- K+ NMT 10 Superfast Tablet Disintegration
APION DM44 Polacrilin Potassium USP Powder -COO- K+ NMT 10 Tablet Disintegration
APION DT44 Polacrilin Potassium USP Powder -COO- K+ NMT 10 Tablet Disintegration / Taste Masking

Why APION?

APION provides innovative solutions for pharmaceutical formulations where traditional excipients fall short. As a Taste masking polymer, it enhances patient compliance by improving palatability and stability. APION also ensures superior disintegration control, formulation reproducibility, and versatility across tablets and suspensions, making it a reliable choice in oral excipients for modern drug delivery.

FAQs

APION polymers function as a Taste masking polymer by binding bitter-tasting drug molecules and preventing their immediate release in the oral cavity. This is especially useful in pediatric and geriatric formulations, such as azithromycin taste masking applications.

APION is available in different grades tailored for specific functions such as cholestyramine powder alternatives, suspension-based Taste masking polymer systems, and solid oral disintegration excipients. Each type is designed for precise formulation needs.

The moisture content of APION polymers is tightly controlled to maintain stability and prevent degradation, similar to quality parameters observed in vitamin b12 USP and other pharmaceutical-grade ingredients.

Yes, APION polymers are versatile and can be incorporated into both solid tablets and suspension formulations. They act effectively as oral excipients, supporting taste masking, disintegration, and release modification for a wide range of drugs including zinc drug formulations where zinc gluconate is for supplementation and therapeutic benefits.

Absolutely. APION polymers are recognized as safe excipients for pharmaceutical use. Their reproducibility and performance have made them a trusted choice in taste masking, disintegration control, and applications such as cholestyramine powder substitutes, ensuring patient-friendly dosage forms.

By Application

APION T series

  • Key raw material for NICOTINE POLACRILEX USP
  • Stabilization of Vitamin B 12
  • Taste Masking of Bitter drug like,
  • Dextromethorphan HBr
  • Ofloxacin
  • Norfloxacin
  • Dicyclomine HCL
  • Azithromycin Di-Hydrate
  • Cefpodoxime Proxetil

APION D Series

  • As a tablet Disintegrating Agent
  • Taste Masking of Bitter drug like,
  • Ciprofloxacin HCl
  • Roxithromycin
  • Chloroquine Phosphate
  • Zinc Gluconate
  • Pyrimethamine
  • Tadalafil
  • Zinc Sulphate

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