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Ion exchange polymer
The ION exchange cross-linked polymers known as APION have shown to be efficient and secure excipients that give formulation flexibility and a special solution to issues like API disintegration and taste masking. For the purpose of masking taste and promoting patient compliance, suspension formulations include ion exchange polymers. Ion Exchange polymers, with their great performance and reproducibility, also gain prominence in the oral solid disintegration segment over time.
Based on their application, APION’s are categorized in to three range of categories:
Grade | Generic Name | Physical Form | Functional Group | Ionic Form | Moisture Content | Application |
APION T51 | Polacrilex Resin | Powder | -COO- | H+ | NMT 5.0 | Taste Masking of Bitter Drug, Dextometharphan HBr, Psudoefldrive HCl, Norfloxacine, Ofloxacine, Dicyclomine HCl Key raw material for Nicotine Polacrilex USP Stabilization of Vitamine B12 |
APION TA42 | Weak Cationic Exchange Resin | Powder | -COO- | K+ | NMT 10 | Taste Masking of Bitter drugs like Azithromycin Di-Hydrate |
APION TC42 | Weak Cationic Exchange Resin | Powder | -COO- | H+ | NMT 5.0 | Taste Masking of Bitter drugs like cefpodoxime proxeti |
APION Dt44 | Polacrilin Potassium USP | Powder | -COO- | K+ | NMT 10 | Taste Masking of Bitter drug like Ciprofloxacine HCl, Roxithromycine, Chloroquine Phosphate, Zinc Gluconate, Pyrimethamine, Tadalafile, Zinc Sulphate |
Grade | Generic Name | Physical Form | Functional Group | Ionic Form | Moisture Content | Application |
APION A04 | Sodium Polystyrene Sulphonate USP | Buff / Brown Powder | -SO3- | Na+ | NMT 10 | Sustained / Delayed Release of Drugs like Dextromethaphran HBr, Psudoefidrine HCl Treatment of Hyperkalamia |
APION A48 | Calcium Polystyrene Sulphonate BP/JP | Cream Powder | -SO3- | Ca++ | NMT 10 | Sustained / Delayed Release of Drugs like Dextromethaphran HBr, Psudoefidrine HCl Treatment of Hyperkalamia |
APION A50 | Cholestyramine Resin USP | White Powder | -N+ R3 | Cl- | NMT 12 | Cholesterol Reduction |
Grade | Generic Name | Physical Form | Functional Group | Ionic Form | Moisture Content | Application |
APION DF44 | Polacrilin Potassium USP | Powder | -COO- | K+ | NMT 10 | Superfast Tablet Disintegration |
APION DM44 | Polacrilin Potassium USP | Powder | -COO- | K+ | NMT 10 | Tablet Disintegration |
APION DT44 | Polacrilin Potassium USP | Powder | -COO- | K+ | NMT 10 | Tablet Disintegration / Taste Masking |
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