» Methacrylic Acid Copolymers / Coating Polymers
» Pharma Polymers /Thickening Agent
» Heat Transfer Fluid / Aromatic Chemical
| |
| DRUGCOAT L 30D |
|
 Methacrylic Acid Copolymer Dispersion, USP/NF: |
| |
DRUGCOAT L 30D is an aqueous dispersion of an anionic copolymer based on Methacrylic acid. The polymer corresponds to " Methacrylic Acid Copolymer Dispersion" USP / NF It is insoluble in gastric fluid and soluble in a neutral to weakly alkaline milieu by forming salts with alkalis, thus affording ENTERIC film coating which are soluble in intestinal tract at pH 5.5 and above.
|
| Characteristics: |
| |
| Appearance |
Milky white dispersion of low viscosity |
| Odour |
Faint characteristic odour |
| Dry Substance |
30% dry Substance |
| Viscosity |
At 20oC 7 mPa.s |
| Self Life |
2 years |
|
| |
| Characteristics of the film: |
Colourless and transparent films are formed from DRUGCOAT L 30D when plasticizers are present. This film is insoluble below pH 5.0 and also in natural and artificial gastric juices. They are soluble in the neutral to weakly alkaline region of digestive tract, i.e. in the intestines, in pancreatic or intestinal juice, and in buffer solutions above pH 5.5 |
| |
| Application: |
| |
|
| 100% aqueous based enteric film coating gastric fluid resistance |
| Enteric Film Coating of tablets, pellets and granules, colourless and transparent or coloured with pigments can also be used with water |
| Products like Omeprazole, Rabiprazole, Pantoprazole, Sesmoprazole, Seratio peptidase, Diclofenac Sodium, LAB, (for detail process ask for technical package) can be enteric coated with DRUGCOAT L 30D |
| For the production of film coating for lozenges and traches |
| For resistance to gastric juice with delayed drug release in the intestine when thicker layers are applied |
| To isolate porous cores |
| To improve self protection against environmental effects like humidity, light, temperature |
| to retain the active drug stable for a longer duration |
FOR COATING OF PELLETS IN CAPSULE / GRANULES
|
| To provide the perfect enteric property |
| To improve the shelf life of pellets, granules and powders |
| For isolation of incompatible ingredients |
|
| |
| Additives: |
| |
| It is strongly recommended to add 10-20% plasticizer on dry polymer substance into the aqueous dispersion of DRUGCOAT L 30D, to obtain films of adequate flexibility. |
| |
| Glidants like talc, micronized amorphous silica and glycerol monostearate facilitate spray application to the cores. |
| |
| Opaque white or colored coatings can be obtained by adding pigments like titanium dioxide, food colors and iron oxide. |
|
| Storage: |
To be kept well sealed, free from frost, at a temperature not higher than 30oC, preferably at 5oC to 25oC |
| |
| Packaging: |
H.D.P.E. Carboy, 35 kg net,
H.D.P.E. Drum, 200 kg net |
| |
| |
|
